Multiple mutations in a specific gene in a small population.

doi:10.1016/s0764-4469(98)80456-3

Back to search

Article

Multiple mutations in a specific gene in a small population.

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Jul 1998

Feingold J

Abstract excerpt

Hereditary diseases have been reported with relatively high frequency in some small populations. Founder effect and genetic drift, associated or not with selective advantage of heterozygotes in case of recessive diseases, are the main explanations. Therefore, if we consider one population and one...

Topics

Founder Effect
Gene Frequency
Genes, Recessive
Genetic Diseases, Inborn
Genetics, Population
Heterozygote
Humans
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.