Article
Variation of site-specific methylation patterns in the factor VIII (F8C) gene in human sperm DNA.
Human genetics - 1 Aug 1998
Millar D S, Krawczak M, Cooper D N
Abstract excerpt
The methylation status of 12 CpG sites in three exons of the human factor VIII (F8C) gene was examined by bisulphite genomic sequencing of human sperm DNA from 14 European Caucasians and Asians. Different CpG sites were found to vary in their methylation status both within and between individuals. Strand differences in methylation status were also detected at certain sites, a finding that could reflect...
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