Article
Functional brain networks in DYT1 dystonia.
Annals of neurology - 1 Sept 1998
Eidelberg D, Moeller J R, Antonini A, Kazumata K, Nakamura T, Dhawan V, Spetsieris P, deLeon D, Bressman S B, Fahn S
Abstract excerpt
Early-onset idiopathic torsion dystonia (ITD) is an autosomal dominant hyperkinetic movement disorder with incomplete penetrance, associated with a 3 base-pair deletion in the DYT1 gene on chromosome 9q34. To determine the metabolic substrates of brain dysfunction in DYT1 dystonia, we scanned 7 n...
Topics
- Adolescent
- Adult
- Aged
- Brain
- Brain Mapping
- Carrier Proteins
- Dystonia Musculorum Deformans
- Female
- Genotype
- Heterozygote
- Humans
- Male
- Middle Aged
- Molecular Chaperones
- Movement Disorders
- Nerve Net
- Neural Pathways
- Sleep