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Article

Genetic analysis of mecillinam-resistant mutants of Caulobacter crescentus deficient in stalk biosynthesis.

Journal of bacteriology - 1 Oct 1998

Seitz L C, Brun Y V

Abstract excerpt

Stalk synthesis in Caulobacter crescentus is a developmentally controlled and spatially restricted event that requires the synthesis of peptidoglycan at the stalk-cell body junction. We show that the beta-lactam antibiotic mecillinam prevents stalk synthesis by inhibiting stalk elongation. In addition, mecillinam causes an increase in the diameter of the stalk at the stalk-cell body junction. We describe two...

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Identifiers

PMID: 9748460
DOI: 10.1128/JB.180.19.5235-5239.1998
PMCID: PMC107563

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