Article
Noninvasive, in utero imaging of mouse embryonic heart development with 40-MHz echocardiography.
Circulation - 1 Sept 1998
Srinivasan S, Baldwin H S, Aristizabal O, Kwee L, Labow M, Artman M, Turnbull D H
Abstract excerpt
BACKGROUND: The increasing number of transgenic and targeted mutant mice with embryonic cardiac defects has resulted in the need for noninvasive techniques to examine cardiac structure and function in early mouse embryos. We report the first use of a novel 40-MHz ultrasound imaging system in the study of mouse cardiac development in utero. METHODS AND RESULTS: Transabdominal scans of mouse embryos staged between...
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