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Article

QIAamp spin columns as a method of DNA isolation for forensic casework.

Journal of forensic sciences - 1 Sept 1998

Greenspoon S A, Scarpetta M A, Drayton M L, Turek S A

Abstract excerpt

The Detroit Police Crime Lab has historically used Chelex as a method to isolate DNA for amplification and typing of bloodstains at the HLADQA1, PM and D1S80 loci. However, preliminary validation of several STR systems for casework has demonstrated that the Chelex procedure is not the best method of DNA isolation for STR amplifications for our purposes. Long term storage at -20 degrees C in the presence of...

Topics

Alleles
Blood Stains
DNA
DNA Fingerprinting
Freezing
HLA-DQ Antigens
HLA-DQ alpha-Chains
Humans
Minisatellite Repeats
Polymorphism, Genetic
Specimen Handling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9729819

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