Ionizing radiation and genetic risks. VIII. The concept of mutation component and its use in risk estimation for multifactorial diseases.

doi:10.1016/s0027-5107(98)00146-8

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Article

Ionizing radiation and genetic risks. VIII. The concept of mutation component and its use in risk estimation for multifactorial diseases.

Mutation research - 31 Aug 1998

Denniston C, Chakraborty R, Sankaranarayanan K

Abstract excerpt

Multifactorial diseases, which include the common congenital abnormalities (incidence: 6%) and chronic diseases with onset predominantly in adults (population prevalence: 65%), contribute substantially to human morbidity and mortality. Their transmission patterns do not conform to Mendelian expec...

Topics

Adult
Causality
Chronic Disease
Computer Simulation
Genetics, Population
Humans
Infant, Newborn
Infant, Newborn, Diseases
Models, Genetic
Mutation
Radiation, Ionizing
Risk Factors

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