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<i>Escherichia coli</i>O157:H7 Requires Intimin for Enteropathogenicity in Calves

1 Sept 1998

Abstract excerpt

Enterohemorrhagic Escherichia coli (EHEC) strains require intimin to induce attaching and effacing (A/E) lesions in newborn piglets. Infection of newborn calves with intimin-positive or intimin-negative EHEC O157:H7 demonstrated that intimin is needed for colonization, A/E lesions, and disease in cattle. These results suggest that experiments to determine if intimin-based vaccines reduce O157:H7 levels in cattle...

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Identifiers

PMID: 9712821
DOI: 10.1128/iai.66.9.4560-4563.1998

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