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Article

Kaposi's Sarcoma-Associated Herpesvirus-Encoded Oncogenes and Oncogenesis

1 Apr 1998

Abstract excerpt

Molecular biologic studies of Kaposi's sarcoma-associated herpesvirus (KSHV) have identified a number of potential viral oncogenes that may contribute to KSHV-related neoplasia including a D-type cyclin, an IL-6-like cytokine, and a novel member of the interferon regulatory factor family. KSHV is functionally related to other DNA tumor viruses by encoding specific proteins to inhibit pRb, pro-apoptotic, and...

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PMID: 9709306
DOI: 10.1093/oxfordjournals.jncimonographs.a024176

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