Article
Families with autosomal dominant brachydactyly type E, short stature, and severe hypertension.
Annals of internal medicine - 1 Aug 1998
Toka H R, Bähring S, Chitayat D, Melby J C, Whitehead R, Jeschke E, Wienker T F, Toka O, Schuster H, Luft F C
Abstract excerpt
BACKGROUND: Rare, monogenic forms of hypertension may give insight into novel mechanisms relevant to essential hypertension. Autosomal dominant hypertension with brachydactyly has been documented in a single Turkish kindred; the gene was mapped to chromosome 12p. OBJECTIVE: To describe the molecu...
Topics
- Chromosomes, Human, Pair 12
- DNA, Satellite
- Dwarfism
- Fingers
- Genes, Dominant
- Genotype
- Humans
- Hypertension
- Pedigree
- Syndrome
- Toes