Expression of spectrin alphaI/50 hereditary elliptocytosis and its association with the alphaLELY allele.

doi:10.1159/000040860

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Article

Expression of spectrin alphaI/50 hereditary elliptocytosis and its association with the alphaLELY allele.

Acta haematologica - 1 Jan 1998

Bassères D S, Pranke P H, Vicentim D, Costa F F, Saad S T

Abstract excerpt

Hereditary elliptocytosis (HE) is a group of hemolytic anemias characterized by the presence of elliptical erythrocytes. The underlying alterations lie in the proteins of the membrane skeleton. Defects of the alphaI domain of spectrin have been defined based on a decrease in the normal 80-kD alph...

Topics

Adolescent
Adult
Alleles
Brazil
Elliptocytosis, Hereditary
Female
Humans
Male
Pedigree
Spectrin

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