Article
Hepatitis C virus genotypes and the influence of the induction of immunosuppression with anti-thymocyte globulin (ATG) on chronic hepatitis in renal graft recipients.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Jan 1998
Rodrigues A, Pinho L, Lobato L, Queirós A, Castro R, Daniel M, Dias L, Henriques A C, Sarmento A, Guimarães S
Abstract excerpt
Hepatitis C virus (HCV) exhibits a dramatic genetic variability and several mechanisms of immunological response are unable to control hepatic and extrahepatic replication. Genotype 1 b is associated with more severe clinical manifestations and is less responsive to interferon. In addition, we ha...
Topics
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Immunoglobulins, Intravenous
- Kidney Transplantation
- Liver
- Lymphocytes
- Viral Load