Article
Overproduction of encapsulated insecticidal crystal proteins in a Bacillus thuringiensis spo0A mutant.
Bio/technology (Nature Publishing Company) - 1 Jan 1995
Lereclus D, Agaisse H, Gominet M, Chaufaux J
Abstract excerpt
The spo0A gene of Bacillus subtilis encodes the key factor involved in the initiation of sporulation. It was previously shown that the B. thuringiensis (Bt) cryIIIA gene, encoding a toxin active against coleopteran larvae, is overexpressed in an spo0A mutant of B. subtilis. In this paper we describe the construction of a Bt spo0A mutant strain and its use to produce insecticidal crystal proteins. The spo0A gene...
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