Relation between reactivity to the NS-4 region peptides of hepatitis C virus (HCV) and clinical features among patients infected with HCV genotype 1b.

doi:10.1111/j.1348-0421.1998.tb02286.x

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Article

Relation between reactivity to the NS-4 region peptides of hepatitis C virus (HCV) and clinical features among patients infected with HCV genotype 1b.

Microbiology and immunology - 1 Jan 1998

Sakugawa H, Nakasone H, Nakayoshi T, Kawakami Y, Kinjo F, Saito A, Nakayoshi T, Yamashiro A

Abstract excerpt

Nearly all patients infected with hepatitis C virus (HCV) genotype 1b have reactivity to the core (c22-3) or non-structural (NS)-3 region (c33c) protein in a second-generation recombinant immunoblot assay (RIBA-2). However, reactivities to the NS-4 region antigens (5-1-1, c100-3) vary among patie...

Topics

Adult
Aged
Female
Genotype
Hepacivirus
Hepatitis C
Hepatitis C Antibodies
Humans
Immunoenzyme Techniques
Interferon alpha-2
Interferon-alpha
Male
Middle Aged
Polymerase Chain Reaction
RNA, Viral
Recombinant Proteins
Treatment Outcome
Viral Load

Source

Open in PubMed

Identifiers

PMID: 9623917
DOI: 10.1111/j.1348-0421.1998.tb02286.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9623917-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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