Article
Relation between reactivity to the NS-4 region peptides of hepatitis C virus (HCV) and clinical features among patients infected with HCV genotype 1b.
Microbiology and immunology - 1 Jan 1998
Sakugawa H, Nakasone H, Nakayoshi T, Kawakami Y, Kinjo F, Saito A, Nakayoshi T, Yamashiro A
Abstract excerpt
Nearly all patients infected with hepatitis C virus (HCV) genotype 1b have reactivity to the core (c22-3) or non-structural (NS)-3 region (c33c) protein in a second-generation recombinant immunoblot assay (RIBA-2). However, reactivities to the NS-4 region antigens (5-1-1, c100-3) vary among patients. To clarify whether differences in serological reactivities to the NS-4 antigens are associated with the clinical...
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