Article
The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25.
Nature genetics - 1 Jun 1998
Nishimura D Y, Swiderski R E, Alward W L, Searby C C, Patil S R, Bennet S R, Kanis A B, Gastier J M, Stone E M, Sheffield V C
Abstract excerpt
A number of different eye disorders with the presence of early-onset glaucoma as a component of the phenotype have been mapped to human chromosome 6p25. These disorders have been postulated to be either allelic to each other or associated with a cluster of tightly linked genes. We have identified...
Topics
- Abnormalities, Multiple
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 13
- Chromosomes, Human, Pair 2
- Chromosomes, Human, Pair 6
- DNA-Binding Proteins
- Female
- Forkhead Transcription Factors
- Gene Expression
- Glaucoma
- Humans
- Hydro-Lyases