Article
Genotypic and phenotypic changes in the emergence of Escherichia coli O157:H7.
The Journal of infectious diseases - 1 Jun 1998
Feng P, Lampel K A, Karch H, Whittam T S
Abstract excerpt
Escherichia coli O157:H7 is a foodborne pathogen distinguished from typical E. coli by the production of Shiga toxins (Stx) and the inability to ferment sorbitol (SOR) and to express beta-glucuronidase (GUD) activity. An allele-specific probe for the GUD gene (uidA) and multilocus enzyme electrophoresis were used to elucidate stages in the evolutionary emergence of E. coli O157: H7. A point mutation at +92 in...
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