Article
Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin.
British journal of cancer - 1 Apr 1998
Krunic A L, Garrod D R, Madani S, Buchanan M D, Clark R E
Abstract excerpt
Desmosomes are intercellular junctions that have been shown to be down-regulated in certain types of carcinoma and that may play a role in suppression of invasion and metastasis. This paper describes an immunohistochemical study of three types of epidermal neoplasms with monoclonal antibody to de...
Topics
- Animals
- Antibodies, Monoclonal
- Cadherins
- Carcinoma, Squamous Cell
- Cytoskeletal Proteins
- Desmoglein 1
- Desmoglein 2
- Desmogleins
- Desmoplakins
- Desmosomes
- Humans
- Immunohistochemistry
- Keratoacanthoma
- Mice
- Phenotype