Article
Stroke in a neonate heterozygous for factor V Leiden.
Pediatric neurology - 1 Mar 1998
Varelas P N, Sleight B J, Rinder H M, Sze G, Ment L R
Abstract excerpt
Activated protein C resistance is the most common hereditary coagulation abnormality and is caused by the factor V Leiden mutation. A newborn who developed seizures within hours after delivery and was found to have a bihemispheric stroke is described. This patient, determined to be heterozygous for factor V Leiden, is the first reported case of neonatal stroke associated with this common mutation.
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