Article
MTHFR C677T and A1298C polymorphisms and cerebral stroke in two twin gestations.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Apr 2011
Arpino Carla, Compagnone Eliana, Cacciatore Denise, Coniglio Antonella, Castorina Mario, Curatolo Paolo
Abstract excerpt
BACKGROUND: Stroke in pediatric age is a rare event with a multifactorial genesis which could involve genetic factors as methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphism. At the same time, twin gestation with co-twin demise is an important potential risk factor for premature brain damage. PATIENTS AND METHODS: We describe two children presenting with presumed cerebral stroke born from two...
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