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Article

The incidence of cystic fibrosis in Scotland calculated from heterozygote frequencies.

Clinical genetics - 1 Jan 1998

Brock D J, Gilfillan A, Holloway S

Abstract excerpt

The incidence of cystic fibrosis (CF) has previously been calculated from epidemiological surveys and from neonatal screening. With the cloning of the CF gene it has become possible to derive incidence figures from heterozygote frequencies, provided that the distribution of mutant alleles among healthy carriers is the same as among affected people. We have estimated the allele frequencies for four CF mutations,...

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Identifiers

PMID: 9550361
DOI: 10.1034/j.1399-0004.1998.531530109.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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