Prostaglandin Endoperoxide H Synthase (PGHS) Activity and PGHS-1 and -2 Messenger Ribonucleic Acid Abundance in Human Chorion Throughout Gestation and With Preterm Labor1

Abstract excerpt

Term and preterm parturition is associated with elevated intrauterine PG production. Although an increase of PG synthesis by the fetal membranes during term labor is well documented, there is little data available regarding the prostanoid production of these tissues at term, before the spontaneous onset of labor. In the present study, we determined the expression of PG H2 synthase (PGHS), the committing and...

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