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Article

Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase.

Biochimica et biophysica acta - 17 Feb 1998

Hufton S E, Jennings I G, Cotton R G

Abstract excerpt

Phenylalanine hydroxylase (PAH) exists as an equilibrium of dimers and tetramers. However, there is little information concerning the inter- or intra-molecular interactions required for enzyme quaternary structure. It is predicted that the formation of a PAH tetramer will require at least two points of contact per enzyme subunit. Sequence analysis has suggested the existence of a C-terminal domain with...

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Source

Identifiers

PMID: 9540801
DOI: 10.1016/s0167-4838(97)00171-4

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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