Genetic defects in Chediak-Higashi syndrome and the beige mouse.

Abstract excerpt

Chediak-Higashi syndrome (CHS) is a rare, autosomal recessive, multisystem disorder in which severe immune deficits are accompanied by abnormalities of pigmentation, blood clotting, and neurologic function. There is no specific treatment, and without bone marrow transplantation, most patients suc...

Topics

• Animals
• Chediak-Higashi Syndrome
• Disease Models, Animal
• Genes
• Humans
• Mice
• Mutation