Article
The lines gene of Drosophila is required for specific functions of the Abdominal-B HOX protein.
Development (Cambridge, England) - 1 Apr 1998
Castelli-Gair J
Abstract excerpt
The Hox genes encode homeobox transcription factors that control the formation of segment specific structures in the anterior-posterior axis. HOX proteins regulate the transcription of downstream targets acting both as repressors and as activators. Due to the similarity of their homeoboxes it is likely that much of the specificity of HOX proteins is determined by interaction with transcriptional cofactors, but...
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