Article
Isolation and characterization of a neomycin-resistant mutant of Methanobacterium thermoautotrophicum with a lesion in Na+-translocating ATPase (synthase).
FEBS letters - 22 Dec 1997
Smigán P, Polák P, Majernik A, Greksák M
Abstract excerpt
A mutant of Methanobacterium thermoautotrophicum with a lesion in membrane Na+-translocating ATPase (synthase) was isolated. The total ATPase activity in permeabilized cells of this mutant was elevated three-fold as compared with the wild-type strain. In contrast to wild-type cells, mutant ATPase...
Topics
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Anti-Bacterial Agents
- Cation Transport Proteins
- Cell Membrane
- Cell Membrane Permeability
- Dicyclohexylcarbodiimide
- Drug Resistance, Microbial
- Hydrogen-Ion Concentration
- Methane
- Methanobacterium
- Mutation
- Neomycin
- Sodium