Article
Altered intestinal macrophage phenotype in ovine paratuberculosis.
Research in veterinary science - 1 Jan 2000
Alzuherri H M, Little D, Clarke C J
Abstract excerpt
The expression of macrophage surface markers that are likely to be important in antigen presentation and cell interactions was examined in normal sheep and those with clinical paratuberculosis. Immunohistological studies demonstrated that intestinal macrophages in diseased sheep expressed MHC class II, LFA-1 and CR4 antigens weakly compared with normal tissues. Reverse transcriptase-polymerase chain reaction...
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