Article
YscM1 and YscM2, two Yersinia enterocolitica proteins causing downregulation of yop transcription.
Molecular microbiology - 1 Nov 1997
Stainier I, Iriarte M, Cornelis G R
Abstract excerpt
Synthesis of the Yop proteins by yersiniae is downregulated when secretion is prevented by closure or destruction of the contact (type III) secretion channel. In Yersinia pseudotuberculosis, a mutation in the IcrQ gene, encoding a secreted protein, reduces this feedback inhibition mechanism. Surprisingly, mutation in the yscM gene, the IcrQ homologue in Y. enterocolitica, does not lead to the same deregulated...
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