Article
The role of a triplet repeat sequence of the very low density lipoprotein receptor gene in plasma lipid and lipoprotein level variability in humans.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997
Helbecque N, Dallongeville J, Codron V, Arveiler D, Ruidavets J B, Evans A, Cambien F, Fruchart J C, Amouyel P
Abstract excerpt
The biological role of the very low density lipoprotein receptor (VLDL-R) in humans is not yet elucidated. This cellular receptor binds apolipoprotein E (apoE)-containing lipoparticles and is mainly expressed in peripheral tissues. The VLDL-R gene contains a polymorphic triplet (CGG) repeat located 19 bp upstream of the initiation codon. We explored the allelic distribution of this repeat in 1384 subjects of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
