No founder effect detected in Jewish Ashkenazi patients with fragile-X syndrome.

doi:10.1007/s004390050611

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Article

No founder effect detected in Jewish Ashkenazi patients with fragile-X syndrome.

Human genetics - 1 Dec 1997

Pesso R, Barkai G, Ravia Y, Gak E, Frydman M, Goldman B, Friedman E

Abstract excerpt

Several studies on small homogenous populations suggested that fragile-X syndrome originated from a limited number of founder chromosomes. The Israeli Jewish population could serve as an adequate model for tracing a founder effect due to the unique ethnic makeup and traditional lifestyle. Further...

Topics

Europe
Founder Effect
Fragile X Syndrome
Genetic Markers
Genotype
Haplotypes
Humans
Israel
Jews
Male
Polymerase Chain Reaction

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