Article
[Glucocorticoid-induced apoptosis of human gastric epithelial cells transfected with p53 genes].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 1996
Zhang J, Ke Y, Ning T
Abstract excerpt
To investigate the apoptosis-inducing effect of glucocorticoid on gastric epithelial cell expressing different p53 genes, a human gastric epithelial cell line-GES-1 was transfected with either wild type or mutant p53 cDNA in vitro. The cells were treated with hydrocortisone in a concentration range of 0.2-0.8 g/L. Apoptotic cells were found in those transfectants. The apoptotic response of the wild-type...
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