Article
Low apolipoprotein E epsilon4 allele frequency in the population of Catalonia (Spain) determined by PCR-RFLP and Laser fluorescent sequencer.
European journal of epidemiology - 1 Oct 1997
Gené M, Moreno P, Ezquerra M, Prat A, Huguet E, Adroer R, Oliva R
Abstract excerpt
Specific apolipoprotein E alleles have been associated in the last few years with several diseases using appropriate controls. However, these control groups are rarely representative of the general population since they correspond either to aged or healthy control groups (and thus depleted of pathological alleles). For this reason it is difficult at present to compare population allelic frequencies in different...
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