Article
Infections with Pseudomonas aeruginosa in patients with cystic fibrosis.
Behring Institute Mitteilungen - 1 Feb 1997
Tümmler B, Bosshammer J, Breitenstein S, Brockhausen I, Gudowius P, Herrmann C, Herrmann S, Heuer T, Kubesch P, Mekus F, Römling U, Schmidt K D, Spangenberg C, Walter S
Abstract excerpt
The lung infection with Pseudomonas aeruginosa is regarded as one of the major causes of health decline in patients with cystic fibrosis (CF). The CF host response to the persistent bacterial antigen load in the endobronchiolar lumen is characterized by a pronounced humoral response, local production of cytokines, influx of neutrophils into the lung and a protease-protease inhibitor imbalance predominantly...
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