Article
A new locus for hemiplegic migraine maps to chromosome 1q31.
Neurology - 1 Nov 1997
Gardner K, Barmada M M, Ptacek L J, Hoffman E P
Abstract excerpt
A single familial hemiplegic migraine locus has been previously mapped to 19p13.1 and associated with mutations in a calcium channel gene (CACNL1A4). We describe a new 39-member four-generation family from Wyoming of German-Native American descent with autosomal dominant familial hemiplegic migraine that is not linked to the chromosome 19p locus. Affected individuals showed a stereotypic pattern of migrainous...
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