Article
Localized reversible frameshift mutation in an adhesin gene confers a phase-variable adherence phenotype in mycoplasma.
Molecular microbiology - 1 Sept 1997
Zhang Q, Wise K S
Abstract excerpt
The variable adherence-associated (Vaa) antigen of Mycoplasma hominis is an abundant surface lipoprotein adhesin that may mediate important interactions of this wall-less prokaryotic pathogen with the human host. Extensive mutational variation of Vaa size, as well as sequence and antigenic diverg...
Topics
- Adhesins, Bacterial
- Amino Acid Sequence
- Antigenic Variation
- Bacterial Proteins
- Base Sequence
- Cell Adhesion
- Clone Cells
- Frameshift Mutation
- Gene Expression
- Gene Rearrangement
- Genes, Bacterial
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mycoplasma hominis
- Open Reading Frames
- Phenotype
- Poly A