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Article

Localized reversible frameshift mutation in an adhesin gene confers a phase-variable adherence phenotype in mycoplasma.

Molecular microbiology - 1 Sept 1997

Zhang Q, Wise K S

Abstract excerpt

The variable adherence-associated (Vaa) antigen of Mycoplasma hominis is an abundant surface lipoprotein adhesin that may mediate important interactions of this wall-less prokaryotic pathogen with the human host. Extensive mutational variation of Vaa size, as well as sequence and antigenic divergence, has been described previously. Using a series of clonal isolates representing an isogenic lineage of variants...

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PMID: 9364912
DOI: 10.1111/j.1365-2958.1997.mmi509.x

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