RNA processing and clinical variability in neurofibromatosis type I (NF1).

doi:10.1093/hmg/6.10.1707

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Article

RNA processing and clinical variability in neurofibromatosis type I (NF1).

Human molecular genetics - 1 Jan 1997

Skuse G R, Cappione A J

Abstract excerpt

Neurofibromatosis type 1 (NF1) is a common genetic disorder which predisposes affected individuals to a variety of clinical features including tumors of the central and peripheral nervous systems. The product of the NF1 gene, neurofibromin, is a tumor suppressor which most likely acts through the...

Topics

Alleles
Alternative Splicing
Genes, Tumor Suppressor
Humans
Neurofibromatosis 1
Neurofibromin 1
Protein Biosynthesis
Proteins
RNA Editing
RNA, Messenger
Transcription, Genetic

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