Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine.

doi:10.1089/thy.1997.7.587

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Article

Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine.

Thyroid : official journal of the American Thyroid Association - 1 Aug 1997

Mendive F M, Rossetti L C, Vassart G, Targovnik H M

Abstract excerpt

We analyzed thyroglobulin (Tg) reverse transcription polymerase chain reaction (RT-PCR) products from three congenital goiters and three normal thyroid tissues by Taq I digestion. Tg coding sequences were amplified from position 57 to 8448 in 12 amplification fragments. A Taq I restriction fragme...

Topics

Adenine
Alleles
Animals
Arginine
Cattle
Gene Frequency
Genetic Variation
Glutamine
Goiter
Guanine
Humans
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
RNA-Directed DNA Polymerase
Rats
Thyroglobulin
Thyroid Gland

Source

Open in PubMed

Identifiers

PMID: 9292947
DOI: 10.1089/thy.1997.7.587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9292947-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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