Article
Development of polyarthritis after insertion of silicone breast implants followed by remission after implant removal in 2 HLA-identical sisters bearing rheumatoid arthritis susceptibility genes.
The Journal of rheumatology - 1 Sept 1997
Meier L G, Barthel H R, Seidl C
Abstract excerpt
We describe 2 HLA-identical sisters who both received silicone breast implants and subsequently developed polyarticular arthritis and neurologic symptoms. In both patients, HLA typing revealed 3 alleles typically associated with rheumatic diseases: HLA-DRB1*0405 and HLA-DQB1*0302 (associated with RA), and HLA-DRB4*01 (associated with mixed connective tissue disease and autoimmune reactions in patients with...
Topics
- Arthritis, Rheumatoid
- Arthrography
- Brain Diseases
- Breast Implants
- Female
- Finger Joint
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Mammaplasty
- Middle Aged
- Reoperation
- Silicones
- Synovitis
- Wrist Joint