Article
[Effect of TRA-system of plasmids RP4 and R68.45 on pseudomonas mallei virulence].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1997
Verevkin V V, Volozhantsev N V, Miakinina V P, Svetoch E A
Abstract excerpt
In Pseudomonas mallei, spontaneous mutants (Tra- mutants) of the plasmids RP4 and R68.45, losing the ability to transfer at conjugation are formed. The plasmids RP4 and R68.45 with Tra(+)-phenotype caused a decrease in P. mallei virulence for laboratory animals. At the same time, Tra- mutants of these plasmids do not affect P. mallei virulence. The insertion of DNA fragment of about 1900 bp into the plasmid...
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