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Article

Osmotic balance regulates cell fusion during mating in Saccharomyces cerevisiae.

The Journal of cell biology - 8 Sept 1997

Philips J, Herskowitz I

Abstract excerpt

Successful zygote formation during yeast mating requires cell fusion of the two haploid mating partners. To ensure that cells do not lyse as they remodel their cell wall, the fusion event is both temporally and spatially regulated: the cell wall is degraded only after cell-cell contact and only in the region of cell-cell contact. To understand how cell fusion is regulated, we identified mutants defective in cell...

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Identifiers

PMID: 9281576
DOI: 10.1083/jcb.138.5.961
PMCID: PMC2136759

Genes

GPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Osmotic balance regulates cell fusion during mating in Saccharomyces cerevisiae.PMID 9281576Read ↗

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Fig1p facilitates Ca2+ influx and cell fusion during mating of Saccharomyces cerevisiae.Semantic proximity Read ↗

The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism.Semantic proximity Read ↗

Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.Semantic proximity Read ↗

Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating.Semantic proximity Read ↗

Cell fusion during yeast mating requires high levels of a-factor mating pheromone.Semantic proximity Read ↗

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Prm1 prevents contact-dependent lysis of yeast mating pairs.Semantic proximity Read ↗

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