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Article

Restoration of wild-type virulence to Tri5 disruption mutants of Gibberella zeae via gene reversion and mutant complementation.

Microbiology (Reading, England) - 1 Aug 1997

Proctor Robert H, Hohn Thomas M, McCormick Susan P

Abstract excerpt

Gibberella zeae is a pathogen of small grain crops and produces trichothecene mycotoxins in infected host tissue. The role of trichothecenes in the virulence of G. zeae was previously investigated using trichothecene-non-producing mutants that were generated via transformation-mediated disruption of a gene (Tri5) that encodes the first enzyme in the trichothecene biosynthetic pathway. The mutants were less...

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Identifiers

PMID: 9274012
DOI: 10.1099/00221287-143-8-2583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Restoration of wild-type virulence to Tri5 disruption mutants of Gibberella zeae via gene reversion and mutant complementation.PMID 9274012Read ↗

Analysis of aberrant virulence of Gibberella zeae following transformation-mediated complementation of a trichothecene-deficient (Tri5) mutant.Semantic proximity Read ↗

Genetic analysis of the role of trichothecene and fumonisin mycotoxins in the virulence of FusariumSemantic proximity Read ↗

Relevance of trichothecenes in fungal physiology: disruption of tri5 in Trichoderma arundinaceum.Semantic proximity Read ↗

Transcriptome analysis of trichothecene-induced gene expression in barley.Semantic proximity Read ↗

The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis.Semantic proximity Read ↗

Genetic bases for variation in structure and biological activity of trichothecene toxins produced by diverse fungi.Semantic proximity Read ↗

Tri1 encodes the cytochrome P450 monooxygenase for C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporotrichioides and resides upstream of another new Tri gene.Semantic proximity Read ↗

Fusarium graminearum TRI14 is required for high virulence and DON production on wheat but not for DON synthesis in vitro.Semantic proximity Read ↗

Activation of biosynthetic gene clusters by the global transcriptional regulator TRI6 in Fusarium graminearumSemantic proximity Read ↗

A Novel Trichothecene Toxin Phenotype Associated with Horizontal Gene Transfer and a Change in Gene Function in Fusarium.Semantic proximity Read ↗

Tri1 in Fusarium graminearum encodes a P450 oxygenase.Semantic proximity Read ↗

Targeting Trichothecene Biosynthetic Genes.Semantic proximity Read ↗

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