Article
Clinical management of patients with the long QT syndrome: drugs, devices, and gene-specific therapy.
Pacing and clinical electrophysiology : PACE - 1 Aug 1997
Moss A J
Abstract excerpt
The familial long QT syndrome (LQTS) is now recognized as a genetic channelopathy with a propensity to arrhythmogenic syncope and sudden death. Three genetic mutations have been identified that involve the slow and fast delayed potassium rectifier currents and the sodium current. Distinctive ECG-T wave phenotypes are associated with each of the three genotypes. Current day therapy includes: beta-adrenergic...
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