Article
Complete androgen insensitivity syndrome. Molecular characterization in two Chinese women.
The Journal of reproductive medicine - 1 Jul 1997
Ko T M, Yang Y S, Wu M Y, Kao C H, Hsu P M, Chuang S M, Lee T Y
Abstract excerpt
OBJECTIVE: To study the molecular basis of complete androgen insensitivity syndrome (AIS). STUDY DESIGN: The coding region of the human androgen receptor (hAR) gene in two women with AIS was amplified with polymerase chain reaction using 12 pairs of oligonucleotide primers and then sequenced with a dye terminator method. RESULTS: Both patients had mutation in exon E of the androgen-binding domain. In one patient,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.