Increased diversity within the HLA-A*66 group: implications for matching in unrelated bone marrow transplantation.

doi:10.1111/j.1399-0039.1997.tb02840.x

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Increased diversity within the HLA-A*66 group: implications for matching in unrelated bone marrow transplantation.

Tissue antigens - 1 Jul 1997

Binder T, Wehling J, Huhn D, Blasczyk R

Abstract excerpt

We have identified a new A*66 allele (A*6603) in three related individuals, an Arabic patient suffering from acute myeloid leukemia and two of her relatives. The A*66 alleles differ in three amino acid residues at positions 70, 90 and 163. The closer relationship between A*6602 and A*6603, which only differ at amino acid 70, replacing GLN with HIS, suggests that the alloreactive potential in this mismatch...

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Increased diversity within the HLA-A*66 group: implications for matching in unrelated bone marrow transplantation.

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