Article
Prenatal diagnosis of the thalassaemia syndromes by rapid DNA analytical methods.
Molecular human reproduction - 1 Jun 1997
Kanavakis E, Traeger-Synodinos J, Vrettou C, Maragoudaki E, Tzetis M, Kattamis C
Abstract excerpt
Prenatal diagnostic strategies applied today are based mainly on polymerase chain reaction (PCR) analytical protocols. In Greece a wide range of mutations underlie the thalassaemic haemoglobinopathies, and consequently a variety of PCR-based methods are required to facilitate diagnosis of all pot...
Topics
- Alleles
- Base Sequence
- DNA Mutational Analysis
- DNA Primers
- Evaluation Studies as Topic
- Female
- Gene Frequency
- Genotype
- Globins
- Greece
- Humans
- Male
- Polymerase Chain Reaction