Ethnic differences in interferon-alpha allele frequencies.

Abstract excerpt

Interferon-alpha (IFN-alpha) is a protein family controlled by altogether 26 different IFN-alpha genes. We have previously described an SspI polymorphism in the IFN A17 gene and an association between the SspI A2 allele and nasopharyngeal cancer. In this paper we present data on ethnic differences with respect to IFN A17 SspI allele frequencies. Thus the frequency of the SspI A1 allele was high in two different...

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