Article
Involvement of osmo-sensitive calcium influx in human sperm activation
1 Jan 1996
Abstract excerpt
Mammalian spermatozoa must undergo capacitation and acrosome reaction before fertilization. To date, the precise mechanisms regulating these complex processes are not well understood but it is generally agreed that they involve an influx of calcium from the extracellular space through, as yet, poorly characterized plasma membrane pathways. Here we present evidence for a novel mechanism to increase intracellular...
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