Article
[Sickle cell anemia and malaria--interferences].
Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) - 1 Jan 2000
Năşcuţiu A M
Abstract excerpt
Usually in a population the frequency of lethal recessive genes decreases by eliminating the homozygous individuals. In sickle cell disease the decrease of the frequency of mutant recessive genes does not take place. The fact that a gene which in the homozygous state expressed a serious clinical picture reaches a high frequency in a population can be explained only by a process of natural selection that would...
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