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Article

High genetic instability of heterochromatin after transposition of the LINE-like I factor in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 1997

Dimitri P, Arcà B, Berghella L, Mei E

Abstract excerpt

In the present work, we have asked whether a group of 13 essential genes mapping to the heterochromatin of Drosophila melanogaster chromosome 2 are mutable following transposition of the I factor during I-R hybrid dysgenesis. We found that the frequency of lethal events mapping to chromosome 2 heterochromatin is surprisingly high, despite the low density of genetic functions identified in this region compared...

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Identifiers

PMID: 9223313
DOI: 10.1073/pnas.94.15.8052
PMCID: PMC21555

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