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Article

Testosterone Regulates Apoptosis in Adult Human Seminiferous Tubules<i>in Vitro</i><sup>1</sup>

1 Jul 1997

Abstract excerpt

In the present study an in vitro model was developed and characterized for evaluation of the role of apoptosis in adult human testes. The samples came from adult men undergoing orchidectomy for prostate or testicular cancer. Segments of seminiferous tubules were isolated and incubated under serum-free conditions in the absence or presence of testosterone. Apoptosis was assessed by low mol wt DNA fragmentation...

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PMID: 9215313
DOI: 10.1210/jcem.82.7.4044

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