Neonatal screening for cystic fibrosis in the Trent region (UK): two-stage immunoreactive trypsin screening compared with a three-stage protocol with DNA analysis as an intermediate step.

doi:10.1177/096914139700400109

Article

Neonatal screening for cystic fibrosis in the Trent region (UK): two-stage immunoreactive trypsin screening compared with a three-stage protocol with DNA analysis as an intermediate step.

Journal of medical screening - 1 Jan 1997

Pollitt R J, Dalton A, Evans S, Hughes H N, Curtis D

Abstract excerpt

OBJECTIVES: To assess neonatal screening for cystic fibrosis using immunoreactive trypsin, either alone or in conjunction with DNA analysis for the delta F508 mutation. A novel three-stage screening protocol was compared with the previously introduced two-stage immunoreactive trypsin-DNA protocol...

Topics

Cystic Fibrosis
Heterozygote
Humans
Infant, Newborn
Longitudinal Studies
Mutation
Neonatal Screening
Sensitivity and Specificity
Trypsin
United Kingdom

Neonatal screening for cystic fibrosis in the Trent region (UK): two-stage immunoreactive trypsin screening compared with a three-stage protocol with DNA analysis as an intermediate step.

Abstract excerpt

Topics

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